Ithebhulethi yeDoxycycline hydrochloride yeekati kunye nezinja

Inkcazelo emfutshane:

Ukusuleleka kweebhaktheriya ezintle, iibhaktheriya ezimbi kunye ne-mycoplasma. Izifo zokuphefumula (i-mycoplasma pneumonia, i-chlamydia pneumonia, i-feline nasal branch, isifo se-calicivirus, i-canine distemper). I-Dermatosis, inkqubo ye-genitourinary, usulelo lwesisu, njl.


  • Ukusetyenziswa kunye nedosi:Kulawulo lwangaphakathi: idosi enye, i-5 ~ 10mg nge-1kg ubunzima bomzimba wezinja kunye neekati. Isetyenziswe kanye ngosuku ngeentsuku ezi-3-5.
  • Inkcazo:200mg/ithebhulethi
  • Iinkcukacha zeMveliso

    Iithegi zeMveliso

    Isithako esiphambili: Doxycycline hydrochloride

    Iinkcazelo ngeempawu: Le mveliso iluhlaza okhanyayo.

    Inyathelo lePharmacological:

    Pharmacodynamics:Le mveliso yi-tetracycline ebanzi ye-antibiotic ene-antibacterial effect ebanzi. Iibhaktheriya ezinovakalelo ziquka iibhaktiriya zeGram-positive ezifana nepneumococcus, streptococcus, some staphylococcus, anthrax, tetanus, corynebacterium kunye nezinye iibhaktiriya ezingeGam-negative ezifana neEscherichia coli, Pasteurella, Salmonella, Brucella kunye neHaemophilus, Klebsiterella kunye ne-meliophilus. Kwakhona kunokuthintela i-Rickettsia, i-mycoplasma kunye ne-spirochaeta kwinqanaba elithile.

    I-Pharmacokinetics:Ukufunxa ngokukhawuleza, impembelelo encinci ngokutya, i-bioavailability ephezulu. Ugxininiso lwegazi olusebenzayo lugcinwa ixesha elide, i-tissue permeability yomelele, ukusabalalisa kubanzi, kwaye kulula ukungena kwiseli. Umthamo obonakalayo obonakalayo wokuhanjiswa kwizinja malunga ne-1.5L/kg. Izinga eliphezulu lokubophelela kwiprotheyini kwizinja 75% ukuya kuma-86%. Inxalenye engasebenziyo nge-chelation emathunjini, i-75% yedosi yenja ikhutshwe ngale ndlela. Ukukhutshwa kwezintso kuphela malunga ne-25%, ukukhutshwa kwebiliary kungaphantsi kwe-5%. Isiqingatha sobomi benja malunga neeyure ezili-10 ukuya kwezili-12.

    Ukudibana kweziyobisi:

    (1) Xa ithathwa nge-sodium bicarbonate, inokunyusa ixabiso le-pH esiswini kunye nokunciphisa ukufunxa kunye nomsebenzi wale mveliso.

    (2) Le mveliso inokwenza ii-complexes ezine-divalent kunye ne-trivalent cations, njl., Ngoko ke xa zithathwa kunye ne-calcium, i-magnesium, i-aluminium kunye nezinye i-antacids, iziyobisi ezine-iron okanye ubisi kunye nokunye ukutya, ukufunxa kwabo kuya kuncipha, kubangele ukunciphisa uxinzelelo lweziyobisi lwegazi.

    (3) Ukusetyenziswa okufanayo kunye ne-diuretics enamandla efana ne-furthiamide kunokunyusa umonakalo wezintso.

    4

    Iimpawu:

    Ukusuleleka kweebhaktheriya ezintle, iibhaktheriya ezimbi kunye ne-mycoplasma. Izifo zokuphefumula (i-mycoplasma pneumonia, i-chlamydia pneumonia, i-feline nasal branch, isifo se-calicivirus, i-canine distemper). I-Dermatosis, inkqubo ye-genitourinary, usulelo lwesisu, njl.

    Ukusetyenziswa kunye nedosi:

    Doxycycline. Kulawulo lwangaphakathi: idosi enye, i-5 ~ 10mg nge-1kg ubunzima bomzimba wezinja kunye neekati. Isetyenziswe kanye ngosuku ngeentsuku ezi-3-5. Okanye njengoko kumiselwe ngugqirha. Kunconywa ukuthatha emva kokutya kunye nokusela amanzi amaninzi emva kokulawulwa komlomo.

    Isilumkiso:

    (1) Akukhuthazwa kwizinja kunye neekati ngaphantsi kweeveki ezintathu ngaphambi kokubeleka, ukuncelisa, kunye nenyanga eyi-1 ubudala.

    (2) Sebenzisa ngokuqaphela kwizinja kunye neekati ezinesibindi esibi kunye nokungasebenzi kakuhle kwezintso.

    (3) Ukuba ufuna ukuthatha izongezelelo ze-calcium, izongezelelo zentsimbi, iivithamini, i-antacids, i-sodium bicarbonate, njl. ngexesha elifanayo, nceda ubuncinane i-2h interval.

    (4) Akuvumelekanga ukusebenzisa i-diuretics kunye ne-penicillin.

    (5) Ukudibanisa ne-phenobarbital kunye ne-anticoagulant iya kuchaphazela umsebenzi womnye nomnye.

    Impendulo engalunganga:

    (1) Kwizinja kunye neekati, iziphumo ezibi kakhulu ze-doxycycline yomlomo kukuhlanza, uhudo, kunye nokunciphisa ukutya. Ukuze kuthomalaliswe iziphumo ezibi, akukho kuncipha kubalulekileyo ekufunxeni kweziyobisi kwabonwa xa kuthathwa kunye nokutya.

    (2) I-40% yezinja eziphathwayo ziye zanda ukwanda kwe-enzymes enxulumene nomsebenzi wesibindi (i-alanine aminotransferase, i-conglutinase esisiseko). Ukubaluleka kweklinikhi kokunyuka komsebenzi wesibindi ezinxulumene ne-enzymes akucaci.

    (3) I-doxycycline yomlomo ingabangela i-esophageal stenosis kwiikati, ezifana neepilisi zomlomo, kufuneka zithathwe ubuncinane nge-6ml yamanzi, ingomile.

    (4) Unyango nge-tetracycline (ingakumbi ixesha elide) kunokukhokelela ekugqithiseni kweebhaktheriya ezingenabuhlungu okanye i-fungi (usulelo oluphindwe kabini).

    Ekujoliswe kuko: Kuphela iikati nezinja.

    Inkcazo: 200mg/ithebhulethi






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