Isalathiso:Isetyenziselwa ukunyanga usulelo lwentakumba kunye namakhalane kumphezulu wenja, kwaye inokunceda kunyango lwe-alergic dermatitis ebangelwa ziintakumba.
Ixesha lokuQinisekisa:Iinyanga ezingama-24.
AthethaSubude:(1) 112.5mg (2) 250mg (3) 500mg (4)1000mg (5)1400mg)
Ugcino:Ugcino olutywiniweyo lungaphantsi kwe-30℃.
Umthamo
Izilumkiso:
1. Le mveliso akufuneki isetyenziswe kumantshontsho angaphantsi kweeveki ezisi-8 okanye izinja ezinobunzima obungaphantsi kwe-2kg.
2. Musa ukusebenzisa izinja aleji kule mveliso.
3. Ixesha le-dosing yale mveliso aliyi kuba ngaphantsi kweeveki ezi-8.
4.Ungatyi, usele okanye utshaye ngelixa uhambisa ichiza. Hlamba izandla ngokucokisekileyo ngesepha namanzi ngoko nangoko emva kokuba udibane nale mveliso.
5.Gcina kwindawo ekungafikeleli kuyo abantwana.
6.Nceda ujonge ukuba iphakheji iphelele na phambi kokusetyenziswa. Ukuba yonakele, ungayisebenzisi.
I-7.Izidakamizwa zezilwanyana ezingasetyenziswanga kunye nezinto zokupakisha kufuneka zilahlwe ngokuhambelana nemimiselo yendawo.
Inyathelo lePharmacologic:
Ingasetyenziselwa ukuzala izinja, ezimithiyo nezincancisayo ezimazi.
I-Fluralaner inezinga eliphezulu lokubopha i-protein ye-plasma kwaye inokukhuphisana namanye amachiza anezinga eliphezulu lokubopha iprotheni, njenge-non-steroidal anti-inflammatory drugs, i-coumarin derivative warfarin, njl. iprotein ebophelelayo phakathi kwe-fluralaner kunye ne-carprofen kunye ne-warfarin. Ulingo lweklinikhi aluzange lufumane ukusebenzisana phakathi kwe-fluralaner kunye neyeza lemihla ngemihla elisetyenziswa kwizinja.
Kwimeko apho kukho ukusabela okumandundu okanye ezinye iziphumo ezimbi ezingachazwanga kule ncwadana, nceda udibane nogqirha wezilwanyana kwangethuba.
Le mveliso yenza ngokukhawuleza kwaye inokunciphisa umngcipheko wokusasazwa kwezifo ezithwala izinambuzane. Kodwa iintakumba kunye namakhalane kufuneka ziqhagamshelane nomninimzi kwaye ziqalise ukutyisa ukuze zibonakale kwisithako esisebenzayo sechiza. Iintakumba (Ctenocephalus felis) zisebenza kwiiyure ezisi-8 emva kokuba sesichengeni, kwaye amakhalane (Ixodes ricinus) asebenza kwiiyure ezili-12 emva kokuba sesichengeni. Ngoko ke, phantsi kweemeko ezimaxongo kakhulu, umngcipheko wokosuleleka kwezifo ngee-parasites awunakukhutshwa ngokupheleleyo.
Ukongeza kokutya ngokuthe ngqo, le mveliso inokuxutywa ekutyeni kwenja yokutya, kwaye uqaphele inja ngexesha lokulawula ukuqinisekisa ukuba inja iginya iyeza.
Ixesha lokurhoxisa:Akufuneki ukuba yenziwe
Amandla epakethi:
Ithebhulethi eyi-1/ibhokisi okanye iipilisi ezi-6/ibhokisi
AembiRinyathelo:
Izinja ezimbalwa kakhulu (1.6%) ziya kuba nokusabela okungephi kunye nokuthatha ixeshana kwesisu, okufana nesifo sorhudo, ukugabha, ukuphelelwa ngumdla wokutya, kunye nezinkcwe.
Kwii-puppies ze-8-9 zeveki ezinobunzima be-2.0-3.6 kg, zanikwa amaxesha angama-5 ubuninzi obuphakanyisiweyo be-fluralaner ngaphakathi, kanye emva kweeveki ze-8, ngamaxesha angama-3, kwaye akukho zithintelo ezibi zabonwa.
Ukulawulwa komlomo ngamaxesha e-3 i-dose ephezulu ephakanyisiweyo ye-fluralaner kwi-Beagles ayizange ifunyanwe ibe nefuthe kwikhono lokuzala okanye ukusinda kwizizukulwana ezilandelayo.
I-Collie yayine-multi-drug resistance gene deletion (MDR1-/-), kwaye yayinyamezeleke ngokulawulwa kwangaphakathi kwamaxesha e-3 i-dose ephezulu ephakanyisiweyo ye-fluralaner, kwaye akukho zimpawu zeklinikhi ezinxulumene nonyango zabonwa.