I-sulfonamides ineenzuzo ze-antibacterial spectrum ebanzi, iipropati ezizinzileyo, ixabiso eliphantsi kunye neentlobo ezahlukeneyo zamalungiselelo onokukhetha kuzo. Isakhiwo esisisiseko se-sulfonamides yi-p-sulfanilamide. Inokuphazamisa ukudityaniswa kwe-folic acid yebhaktiriya kwaye ichaphazele ukukhula kwayo kunye nokuzala, ngaloo ndlela inqanda uninzi lweebhaktheriya zeGram-positive kunye neebhaktheriya ezingalunganga.

Iintsholongwane ezibuthathaka kakhulu kwi-sulfa ziquka: iStreptococcus, Pneumococcus, Salmonella, njl., kunye novelwano oluphakathi kwezi: Staphylococcus, Escherichia coli, Pasteurella, Shigella, Listeria, ezinye i-Actinomyces kunye neTreponema hyodysenteriae Kwakhona buthathaka kwi-sulfonamides; ikwasebenza ngokuchasene neprotozoa ethile efana necoccidia. Iintsholongwane ezibuthathaka kwi-sulfonamides zinokukhula ukuxhathisa.

Ekusetyenzisweni ngokwenene, i-sulfonamides isetyenziswa rhoqo kunye namanye amachiza. Uninzi lweziphumo ezibi zokusetyenziswa kwexesha elide le-sulfonamides zakuqala kukuphazamiseka kwendlela yomchamo, ukungasebenzi kakuhle kwezintso kunye nokuncipha kokutya.

Ukuze unciphise i-toxic and side effects, okokuqala, i-dosage kufuneka ifaneleke, kwaye akufanele inyuswe okanye iyancipha ngokuthanda. Ukuba i-dosage inkulu kakhulu, iya kwandisa ityhefu kunye nemiphumo emibi, kwaye ukuba i-dosage incinci kakhulu, ayiyi kuba nefuthe lonyango kuphela, kodwa iya kubangela ukuba ibhaktheriya ye-pathogenic iphuhlise ukuxhathisa iziyobisi. Okwesibini, sebenzisa kunye nezinye iziyobisi, ezifana ne-amproline kunye ne-sulfonamide synergists, ukunciphisa umthamo. Okwesithathu, ukuba ifomula ivumela, inani elilinganayo le-sodium bicarbonate inokongezwa. Okwesine, iintsholongwane zinokuvelisa amanqanaba ahlukeneyo okuxhathisa amayeza esalfa, ngoko xa zixhathisa iyeza elithile lesulfa, akufanelekanga ukutshintshela kwelinye iyeza lesulfa. Ngokuqhelekileyo, umthamo wokuqala wamachiza e-sulfa kufuneka uphindwe kabini, kwaye emva kwexesha elibukhali, ichiza kufuneka linyanzeliswe ukuba lithathe iintsuku ezi-3-4 ngaphambi kokuba liyeke.